Scott Hickle is the founder and CEO of Throne, a health tech startup building the world’s first smart toilet to help people monitor their gut health, hydration, and urological function through passive, real-time data collection. With a background in engineering and product management, Scott blends deep technical knowledge with a mission-driven approach to preventative health. A Texas native and Austin-based builder, he’s turning one of the last untapped frontiers of health data—the toilet—into a life-saving diagnostic tool. In this episode, Brett sits down with Scott Hickle, founder of Throne, to unpack one of the most ambitious healthtech missions in the game: building a toilet that could help prevent colon cancer, manage IBD, and transform gut health awareness. Scott shares how Throne evolved from a running joke to a startup with the potential to save lives. They dive deep into gut health, the cultural stigma around poop, and how stress, sleep, and food inputs impact digestion. Scott also shares takeaways from his ultra-processed food experiment and lessons from startup life—touching on energy, mission, and building in public. What we cover: - The Origin of Throne - The Gut as a Diagnostic Goldmine - Ultra-Processed Food Experiment - Building a Mission-Driven Startup Timestamps: (00:33) – How Throne was born (05:45) – From math failure to engineer (10:00) – Pain tolerance and entrepreneurship (27:55) – The smart toilet idea emerges (30:40) – Gut health starts in the toilet (36:00) – Why people ignore symptoms (44:50) – Tracking your gut in real time (52:00) – Preventing colon cancer early *** LINKS***Check out our Newsletter - <a href="https://themeatmafia.beehiiv.com/">Food for Thought</a> - to dramatically improve your health this year!Join The Meat Mafia community <a href="https://t.me/+kjtD9vQBh-s5YzFh">Telegram</a> group for daily conversations to keep up with what’s happening between episodes of the show.Connect with Scott: <a href="https://www.instagram.com/scotthickle/">Instagram</a> <a href="https://www.thronescience.com/">Throne </a> Connect with Brett:<a href="https://www.instagram.com/meatmafiabrett/">Instagram</a> <a href="https://x.com/MeatMafiaBrett">X</a>Connect with Harry:<a href="https://www.instagram.com/meatmafiaharry/">Instagram</a> <a href="https://x.com/MeatMafiaHarry">X</a>Connect with Meat Mafia: Instagram - <a href="https://www.instagram.com/meatmafiamedia/">Meat Mafia</a> X - <a href="https://twitter.com/themeatmafiapod">Meat Mafia</a> YouTube - <a href="https://www.youtube.com/channel/UCTadLQ-3Eb58I0Q2hVQjffw">Meat Mafia</a>Connect with Noble Protein: Website - <a href="https://nobleorigins.com/">Noble Protein</a> X - <a href="https://twitter.com/eatnobleorigins">Noble Protein</a> Instagram - <a href="https://www.instagram.com/noble.origins/">Noble Protein</a>AFFILIATES<ol><li><a href="https://drinklmnt.com/meatmafia">LMNT</a> - Electrolyte salts to supplement minerals on low-carb diet</li><li><a href="https://the-carnivore-bar.myshopify.com/mafia">The Carnivore Bar</a> - Use Code 'MEATMAFIA' for 10% OFF - Delicious &amp; convenient Pemmican Bar</li><li><a href="https://perennialpasturesranch.com/?sca_ref=2773923.WJlPpRyTNk">Perennial Pastures</a> - Use CODE 'MEATMAFIA' 10% OFF - Regeneratively raised, grass-fed &amp; grass-finished beef from California &amp; Montana</li><li><a href="https://farrow.life/shop/">Farrow Skincare</a> - Use CODE 'MEATMAFIA' at checkout for 20% OFF</li><li><a href="https://heartandsoil.co/?utm_campaign=&amp;utm_source=&amp;utm_medium=&amp;gclid=CjwKCAiA3KefBhByEiwAi2LDHKDDiMXJ8_C-Zx0rD8xgcK3LvQPcI_R52tbspbh8aVnENt_YJkK2LBoCEfkQAvD_BwE">Heart &amp; Soil</a> - CODE ‘MEATMAFIA’ for 10% OFF - enhanced nutrition to replace daily vitamins!</li><li><a href="http://carnivoresnax.com/">Carnivore Snax</a> - Use CODE 'MEATMAFIA' Crispy, airy meat chips that melt in your mouth. Regeneratively raised in the USA.</li><li><a href="https://eatpluck.com/?ref=MEATMAFIA">Pluck Seasoning</a> - 15% OFF - Nutrient-dense seasoning with INSANE flavor! Use CODE: MEATMAFIA</li><li><a href="https://www.wefeedraw.com/?promoCode=MEATMAFIA25&amp;sscid=41k7_xn0hh&amp;utm_source=ShareASale&amp;utm_medium=affiliate&amp;utm_campaign=3637215&amp;utm_content=41k7_xn0hh">We Feed Raw</a> 25% OFF your first order - ancestrally consistent food for your dog! Use CODE 'MEATMAFIA'</li><li><a href="https://fondbonebroth.com/?rfsn=7100106.da63950&amp;utm_source=affiliate&amp;utm_medium=brett_ender_meat_mafia">Fond Bone Broth</a> - 15% OFF - REAL bone broth with HIGH-QUALITY ingredients! It’s a daily product for us! Use CODE: MAFIA</li><li><a href="https://mauinuivenison.com/">Maui Nui</a>- 15% OFF. Use CODE: MEATMAFIA</li></ol>

#391 Scott Hickle: What Your Poop Says About Your Health